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5-azacytidine-induced protein 2

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Protein Overview: 5-azacytidine-induced protein 2

Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFN-beta promoter activation via TICAM1.

Synonyms: NF-kappa-B-activating kinase-associated protein 1, Nak-associated protein 1, TILP

Gene name: AZI2

Database References

UniProtID GeneID
Homo sapiens A8K3M2 64343
Pongo abelii Q5RD40 100174325
Bos taurus Q3SYW5 767932
Crab-eating macaque Q4R3X1
Rattus norvegicus Q4KMA0 316051
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Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017