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A disintegrin and metalloproteinase with thrombospondin motifs 5

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Protein Overview: A disintegrin and metalloproteinase with thrombospondin motifs 5

Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. May play a role in proteolytic processing mostly during the peri-implantation period.

Synonyms: ADAM-TS 5, ADAM-TS5, ADAMTS-5, ADMP-2, Aggrecanase-2, Implantin

Gene name: Adamts5

Database References

UniProtID GeneID
Mus musculus B2RRX9 23794
Bos taurus Q9TT92
Homo sapiens Q52LV4 11096

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017