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A-kinase anchor protein 5

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Protein Overview: A-kinase anchor protein 5

May anchor the PKA protein to cytoskeletal and/or organelle-associated proteins, targeting the signal carried by cAMP to specific intracellular effectors. Association with to the beta2-adrenergic receptor (beta2-AR) not only regulates beta2-AR signaling pathway, but also the activation by PKA by switching off the beta2-AR signaling cascade.

Synonyms: AKAP-5, A-kinase anchor protein 79 kDa, AKAP 79, H21, cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein

Gene name: AKAP5

Database References

UniProtID GeneID
Homo sapiens A2RRB8 9495
Rattus norvegicus P24587 171026
Mus musculus D3YVF0 238276
Bos taurus P24275 281612

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017