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ABC transporter C family member 5

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Protein Overview: ABC transporter C family member 5

Pump for glutathione S-conjugates. Involved in regulation of K(+) and Na(+) cell content. Mediates resistance to NaCl and Li(+), confers sensitivity to sulfonylurea drugs such as glibenclamide (inducer of stomatal opening), and required for stomatal opening regulation by auxin, abscisic acid (ABA) and external Ca(2+). Transports oestradiol-17-(beta-D-glucuronide) (E(2)17G). Involved in the root auxin content regulation that controls the transition from primary root elongation to lateral root formation. Plays a role in ABA-mediated germination inhibition.

Synonyms: ABC transporter ABCC.5, AtABCC5, ATP-energized glutathione S-conjugate pump 5, Glutathione S-conjugate-transporting ATPase 5, Multidrug resistance-associated protein 5

Gene name: ABCC5

Database References

UniProtID GeneID
Arabidopsis thaliana O65619 839277
Dictyostelium discoideum Q54LE6 8625755

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017