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Achaete-scute homolog 1

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Protein Overview: Achaete-scute homolog 1

Transcriptional regulator. May play a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Essential for the generation of olfactory and autonomic neurons. Involved in the initiation of neuronal differentiation. Mediates transcription activation by binding to the E box (5'-CANNTG-3').

Synonyms: ASH-1, hASH1, Class A basic helix-loop-helix protein 46, bHLHa46

Gene name: Ascl1

Database References

UniProtID GeneID
Rattus norvegicus P19359 64186
Homo sapiens A8K3C4 429
Xenopus laevis Q06234 378517
Mus musculus Q02067

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017