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Actin filament-associated protein 1

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Protein Overview: Actin filament-associated protein 1

Can cross-link actin filaments into both network and bundle structures (By similarity). May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells.

Synonyms: 110 kDa actin filament-associated protein, AFAP-110, Neural actin filament protein, pp110

Gene name: AFAP1

Database References

UniProtID GeneID
Gallus gallus Q90738 374034
Rattus norvegicus Q8VH46 140935
Mus musculus Q3UGX1 70292
Homo sapiens A8K442 60312

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017