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Activating signal cointegrator 1 complex subunit 3

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Protein Overview: Activating signal cointegrator 1 complex subunit 3

3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3, enabling ALKHB3 to process alkylated N3-methylcytosine (3mC) within double-stranded regions. Enhances NF-kappa-B, SRF and AP1 transactivation.

Synonyms: ASC-1 complex subunit p200, ASC1p200, Helicase, ATP binding 1, Trip4 complex subunit p200

Gene name: ASCC3

Database References

UniProtID GeneID
Homo sapiens E7EW23 10973
Gallus gallus F1NTD6
Mus musculus E9PZJ8 77987
Zebrafish E7F5Q7
Rattus norvegicus F1LPQ2
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Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017