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Activin receptor type-2A

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Protein Overview: Activin receptor type-2A

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.

Synonyms: Activin receptor type IIA, ACTR-IIA

Gene name: acvr2a

Database References

UniProtID GeneID
Xenopus laevis P27039 399283
Homo sapiens B2RAB8 92
Rattus norvegicus P38444 29263
Ovis aries Q28560 443304
Bos taurus A5D7L7 281598
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Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017