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Adipocyte enhancer-binding protein 1

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Protein Overview: Adipocyte enhancer-binding protein 1

Isoform 2 may positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation. Isoform 2 may also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness. Can act as a transcriptional repressor.

Synonyms: AE-binding protein 1, Aortic carboxypeptidase-like protein

Gene name: Aebp1

Database References

UniProtID GeneID
Mus musculus O88442 11568
Rattus norvegicus A2RUV9 305494
Homo sapiens Q14113 165

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017