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ADP-ribosylation factor 1

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ADP-ribosylation factor 1 Product Reviews

3 - Good (Publishable / Would use again)
Application: WB
Sample: Human Cell lysate - whole cell (huh-7)
Buffer: Milk: Concentration 5% - Temperature 20°C
Dilution: 1/500

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Protein Overview: ADP-ribosylation factor 1

GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles.

Synonyms: lARF1

Gene names: arf1, arfA, Arf79F, LOC_Os01g59790

Database References

UniProtID GeneID
Schizosaccharomyces pombe (strain 972 / ATCC 24843) P36579 2540899
Chinese cabbage Q96361
Locusta migratoria P35676
Daucus carota P51822
Drosophila melanogaster A4V2B1 40506
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Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017