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ADP-ribosylation factor-like protein 6

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Protein Overview: ADP-ribosylation factor-like protein 6

Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia. May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade. Isoform 2 may be required for proper retinal function and organization.

Synonyms: ADP-ribosylation factor-like protein 6, ADP-ribosylation factor-related protein 1.1

Gene names: arl-6, ARF11

Database References

UniProtID GeneID
Caenorhabditis briggsae A8XSQ6 8584035
Mus musculus O88848 56297
Caenorhabditis elegans Q18510 183311
Bos taurus Q0IIM2 519014
Zebrafish Q5M9P8 494134
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Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017