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Agouti-related protein

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Protein Overview: Agouti-related protein

Plays a role in weight homeostasis. Plays a role in the central control of feeding. Reduces food intake. Inhibits cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Acts primarily on MC3R and MC4R. Has very low activity with MC5R.

Gene name: Agrp

Database References

UniProtID GeneID
Mus musculus O35967 11604
Bos taurus P56413 280987
Sus scrofa Q9TU18 397275
Homo sapiens O00253 181

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017