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Protein Overview: Akirin-2

Forms a complex with YWHAB that acts to repress transcription of DUSP1 (By similarity). Required for embryonic development and the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6.

Synonyms: Fourteen-three-three beta interactant 1, Fourteen-three-three beta interacting-protein 1

Gene name: Akirin2

Database References

UniProtID GeneID
Mus musculus B1AXD8 433693
Bos taurus A8YXY8 614292
Rattus norvegicus Q25C79 297968
Homo sapiens Q53H80 55122

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017