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AKT-interacting protein

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Protein Overview: AKT-interacting protein

Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade.

Synonyms: Fused toes protein homolog

Gene name: aktip

Database References

UniProtID GeneID
Zebrafish Q6P3I9 378716
Salmo salar B5X1G6 100194893
Mus musculus Q3TYE3 14339
Pongo abelii Q5RE48 100171791
Western clawed frog Q28IA3 549957
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Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017