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Alcohol dehydrogenase [NADP(+)]

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Protein Overview: Alcohol dehydrogenase [NADP(+)]

Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs.

Synonyms: 3-DG-reducing enzyme, Aldehyde reductase, Aldo-keto reductase family 1 member A1

Gene names: Akr1a1, ARI

Database References

UniProtID GeneID
Rattus norvegicus P51635 78959
Sporobolomyces salmonicolor P27800
Gallus gallus Q5ZK84 424599
Mus musculus Q9CQI5 58810
Chinese hamster O70473
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Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017