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Allograft inflammatory factor 1

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Protein Overview: Allograft inflammatory factor 1

Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.

Synonyms: AIF-1

Gene name: AIF1

Database References

UniProtID GeneID
Bos taurus Q9BDK2 280989
Sus scrofa P81076
Rattus norvegicus P55009 29427
Macaca mulatta Q5TM25 574115
Homo sapiens A8K406 199
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Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017