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Alpha-2A adrenergic receptor

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Protein Overview: Alpha-2A adrenergic receptor

Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol.

Synonyms: Alpha-2 adrenergic receptor subtype C10, Alpha-2A adrenoreceptor, Alpha-2A adrenoceptor, Alpha-2AAR

Gene name: ADRA2A

Database References

UniProtID GeneID
Homo sapiens B0LPF6 150
Cavia porcellus Q60474
Mus musculus Q01338
Zebrafish Q90WY4
Sus scrofa P18871 399501
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Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017