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Alpha-2B adrenergic receptor

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Protein Overview: Alpha-2B adrenergic receptor

Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is clonidine > norepinephrine > epinephrine = oxymetazoline > dopamine > p-tyramine = phenylephrine > serotonin > p-synephrine / p-octopamine. For antagonists, the rank order is yohimbine > chlorpromazine > phentolamine > mianserine > spiperone > prazosin > alprenolol > propanolol > pindolol.

Synonyms: Alpha-2B adrenoreceptor, Alpha-2B adrenoceptor, Alpha-2BAR

Gene name: ADRA2B

Database References

UniProtID GeneID
Dugong O77713
Equus caballus O77721
Orycteropus afer O19032
Rattus norvegicus P19328 24174
Didelphis marsupialis virginiana O77715
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Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017