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Protein Overview: Alpha-actinin-4

F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.

Synonyms: F-actin cross-linking protein, Non-muscle alpha-actinin 4

Gene name: Actn4

Database References

UniProtID GeneID
Rattus norvegicus Q6P786 63836
Gallus gallus Q90734 396024
Mus musculus P57780 60595
Pongo abelii Q5RCS6 100174343
Homo sapiens O43707 81
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Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017