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Amiloride-sensitive cation channel 1, neuronal

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Protein Overview: Amiloride-sensitive cation channel 1, neuronal

Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate.

Synonyms: Acid-sensing ion channel 2, ASIC2, Amiloride-sensitive brain sodium channel, Amiloride-sensitive cation channel neuronal 1, Brain sodium channel 1, BNC1, BNaC1, Mammalian degenerin homolog

Gene name: ACCN1

Database References

UniProtID GeneID
Homo sapiens Q13553 40
Mus musculus Q5SUU2 11418
Rattus norvegicus O55163 25364
Zebrafish Q708S5 407669

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017