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Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

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Protein Overview: Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.

Synonyms: Multisynthase complex auxiliary component p38, Protein JTV-1

Gene name: AIMP2

Database References

UniProtID GeneID
Chinese hamster Q9WVM7 100682533
Rattus norvegicus Q32PX2 288480
Homo sapiens Q13155 7965
Bos taurus Q0II26 520979
Mus musculus E9QP67 231872

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017