Find a product

Anaphase-promoting complex subunit 1

(Browse other proteins)

See products

Protein Overview: Anaphase-promoting complex subunit 1

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Synonyms: APC1

Gene names: anapc1, APC1, cut4, bimE

Database References

UniProtID GeneID
Dictyostelium discoideum Q54NC6 8625062
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) D6W112 855549
Arabidopsis thaliana Q9FFF9 830439
Schizosaccharomyces pombe (strain 972 / ATCC 24843) O13457 2539639
Mus musculus A2ATQ4 17222
[+] See all

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017