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Anaphase-promoting complex subunit 13

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Protein Overview: Anaphase-promoting complex subunit 13

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Synonyms: APC13, Cylosome subunit 13

Gene names: Anapc13, apc13, SWM1

Database References

UniProtID GeneID
Mus musculus Q8R034 69010
Schizosaccharomyces pombe (strain 972 / ATCC 24843) O74358 2540285
Western clawed frog Q0IJ25 549994
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) D6VSP0 851847
Bos taurus Q2NKV2 614347
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Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017