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Anaphase-promoting complex subunit 16

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Protein Overview: Anaphase-promoting complex subunit 16

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Synonyms: APC16, Cyclosome subunit 16

Gene name: anapc16

Database References

UniProtID GeneID
Xenopus laevis Q6GQ63 443949
Mus musculus Q9CPV2 52717
Bos taurus Q1RMH7 540089
Homo sapiens Q96DE5 119504
Western clawed frog Q28DH5 448194
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Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017