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Anaphase-promoting complex subunit 7

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Protein Overview: Anaphase-promoting complex subunit 7

Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

Synonyms: Cyclosome subunit 7

Gene names: APC7, Anapc7

Database References

UniProtID GeneID
Arabidopsis thaliana C0Z2F9 818495
Mus musculus Q3UBM7 56317
Homo sapiens Q96AC4 51434
Dictyostelium discoideum Q54D58 8628702

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017