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Protein Overview: Angiomotin

Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions.

Gene name: Amot

Database References

UniProtID GeneID
Mus musculus A2AMJ9 27494
Homo sapiens Q4VCS5 154796

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017