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Angiotensin-converting enzyme 2

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Protein Overview: Angiotensin-converting enzyme 2

Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.

Synonyms: ACE-related carboxypeptidase, Angiotensin-converting enzyme homolog, ACEH, Metalloprotease MPROT15

Gene name: ACE2

Database References

UniProtID GeneID
Homo sapiens Q6UWP0 59272
Paguma larvata Q56NL1
Rattus norvegicus Q5EGZ1 302668
Cat Q2PGE2 554349
Bos taurus Q58DD0 784098
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Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017