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APOBEC1 complementation factor

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Protein Overview: APOBEC1 complementation factor

Essential component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in APOB mRNA. Binds to APOB mRNA and is probably responsible for docking the catalytic subunit, APOBEC1, to the mRNA to allow it to deaminate its target cytosine. The complex also protects the edited APOB mRNA from nonsense-mediated decay.

Synonyms: APOBEC1-stimulating protein

Gene name: A1cf

Database References

UniProtID GeneID
Rattus norvegicus Q8CH55 170912
Mus musculus E9QJS8 69865
Homo sapiens A1L4F2 29974
Pongo abelii Q5R9H4 100174508

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017