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Apolipoprotein O

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Protein Overview: Apolipoprotein O

Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL. May be involved in myocardium-protective mechanisms against lipid accumulation.

Synonyms: Protein FAM121B

Gene name: Apoo

Database References

UniProtID GeneID
Mus musculus B1ASQ3 68316
Homo sapiens B2R4K9 79135
Bos taurus Q148H0 513847

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017