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Apoptosis-associated speck-like protein containing a CARD

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Protein Overview: Apoptosis-associated speck-like protein containing a CARD

Promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. May be a component of the inflammasome, a protein complex which also includes NALP2, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.

Synonyms: PYD and CARD domain-containing protein

Gene name: PYCARD

Database References

UniProtID GeneID
Bos taurus Q8HXK9 282846
Mus musculus Q9D2W9 66824
Zebrafish Q9I9N6
Homo sapiens Q96D12 29108

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017