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Arachidonate 5-lipoxygenase-activating protein

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Protein Overview: Arachidonate 5-lipoxygenase-activating protein

Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.

Synonyms: FLAP, MK-886-binding protein

Gene name: ALOX5AP

Database References

UniProtID GeneID
Homo sapiens P20292 241
Sus scrofa P30356
Equus caballus P30353
Rattus norvegicus P20291 29624
Mus musculus P30355 11690
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Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017