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Arf-GAP domain and FG repeat-containing protein 1

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Protein Overview: Arf-GAP domain and FG repeat-containing protein 1

Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.

Synonyms: HIV-1 Rev-binding protein homolog, Nucleoporin-like protein RIP

Gene name: Agfg1

Database References

UniProtID GeneID
Mus musculus O70448 15463
Bos taurus Q2TA45 536149
Rattus norvegicus Q4KLH5 363266
Homo sapiens P52594 3267

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017