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Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2

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Protein Overview: Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2

Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration.

Synonyms: Development and differentiation-enhancing factor 2, Paxillin-associated protein with ARF GAP activity 3, PAG3, Pyk2 C-terminus-associated protein, PAP

Gene name: Asap2

Database References

UniProtID GeneID
Mus musculus Q501K1 211914
Homo sapiens D6W4Y8 8853

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017