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Protein Overview: Artemin

Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut haematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue.

Synonyms: Enovin, Neublastin

Gene name: Artn

Database References

UniProtID GeneID
Rattus norvegicus Q6AYE8 362572
Artemia salina P17720
Mus musculus Q3SXF4 11876
Homo sapiens D3DPY1 9048

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017