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Aryl hydrocarbon receptor

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Protein Overview: Aryl hydrocarbon receptor

Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues.

Synonyms: Ah receptor, AhR

Gene name: AHR

Database References

UniProtID GeneID
Oryctolagus cuniculus O02747 100008995
Western Mediterranean mouse Q8R4S2
Mus musculus molossinus Q8R4S5
Ryukyu mouse Q8R4S7
Delphinapterus leucas Q95LD9
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Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017