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Asialoglycoprotein receptor 1

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Protein Overview: Asialoglycoprotein receptor 1

Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.

Synonyms: ASGP-R 1, ASGPR 1

Gene name: ASGR1

Database References

UniProtID GeneID
Pongo abelii Q5RBQ8 100172364
Homo sapiens P07306 432
Rattus norvegicus P02706 24210
Mus musculus P34927 11889

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017