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Asialoglycoprotein receptor 2

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Protein Overview: Asialoglycoprotein receptor 2

Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.

Synonyms: ASGP-R 2, ASGPR 2, Hepatic lectin R2/3, HL-2, rHL-2

Gene name: Asgr2

Database References

UniProtID GeneID
Rattus norvegicus P08290 29403
Homo sapiens A6NLV8 433
Mus musculus P24721 11890

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017