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ATPase family AAA domain-containing protein 1

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Protein Overview: ATPase family AAA domain-containing protein 1

ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learning and memory. Required for NMDA-stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane; these activities are ATPase-dependent.

Synonyms: Thorase

Gene name: ATAD1

Database References

UniProtID GeneID
Homo sapiens D3DR26 84896
Mus musculus Q3U8V2 67979
Bos taurus A7MB55
Rattus norvegicus B3STU2 309532
Western clawed frog B4F6J6 100216041

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017