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Protein Overview: Atrophin-1

Transcriptional corepressor. Recruits NR2E1 to repress transcription. Promotes vascular smooth cell (VSMC) migration and orientation (By similarity). Corepressor of MTG8 transcriptional repression. Has some intrinsic repression activity which is independent of the number of poly-Asn (polyQ) repeats.

Synonyms: Dentatorubral-pallidoluysian atrophy protein homolog

Gene name: ATN1

Database References

UniProtID GeneID
Pan troglodytes Q5IS70 451803
Homo sapiens P54259 1822
Rattus norvegicus P54258 29515
Mus musculus O35126 13498

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017