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Autophagy protein 5

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Protein Overview: Autophagy protein 5

Required for autophagy. Conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed.

May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.

Synonyms: APG5-like

Gene name: ATG5

Database References

UniProtID GeneID
Coccidioides immitis (strain RS) Q1DP17 4559549
Oryza sativa subsp. indica A2X052
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) Q75BY9 4619665
Sus scrofa Q3MQ04 641362
Dictyostelium discoideum Q54GT9 8627395
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Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017