Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. Binding of AP180 to clathrin triskelia induces their assembly into 60-70 nm coats.
Synonyms: 91 kDa synaptosomal-associated protein, Clathrin coat-associated protein AP180, Phosphoprotein F1-20
Gene names: Snap91, AP180