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Cyclic AMP-dependent transcription factor ATF-2

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Protein Overview: Cyclic AMP-dependent transcription factor ATF-2

Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2/JUN complex.

Synonyms: cAMP-dependent transcription factor ATF-2, Activating transcription factor 2

Gene name: ATF2

Database References

UniProtID GeneID
Gallus gallus O93602 395727
Homo sapiens A1L3Z2 1386
Mus musculus P16951 100047997
Rattus norvegicus Q00969 81647

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017