Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
Synonyms: Autophagy-related cysteine endopeptidase 2B, Autophagin-2B, Autophagy-related protein 4 homolog B, bAut2B
Gene name: ATG4B
|Oryza sativa subsp. japonica||Q7XPW8||4337435|
|Oryza sativa subsp. indica||A2XZ28|
Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017