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Cytosolic carboxypeptidase 1

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Protein Overview: Cytosolic carboxypeptidase 1

Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.

Synonyms: ATP/GTP-binding protein 1, Nervous system nuclear protein induced by axotomy protein 1 homolog

Gene names: AGTPBP1, ccpp-1

Database References

UniProtID GeneID
Homo sapiens B4DIT6 23287
Western clawed frog A9JRL3 100135097
Caenorhabditis elegans O76373 172241
Zebrafish Q4U2V3 554164
Gallus gallus E1C3P4
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Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017