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Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

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Protein Overview: Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes.

Synonyms: P5C dehydrogenase

Gene names: prnC, Aldh4a1, PUT2, DDB_G0283293

Database References

UniProtID GeneID
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) C8VP34 2875278
Rattus norvegicus P0C2X9
Homo sapiens A8K1Q7 8659
Bos taurus A7YWE4 100126042
Zebrafish Q7SY23 394133
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Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017