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Disintegrin and metalloproteinase domain-containing protein 2

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Protein Overview: Disintegrin and metalloproteinase domain-containing protein 2

Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein.

Synonyms: ADAM 2, Fertilin subunit beta, PH-30, PH30, PH30-beta

Gene name: Adam2

Database References

UniProtID GeneID
Rattus norvegicus Q63202 56806
Homo sapiens P78326 2515
Mus musculus Q60718 11495
Oryctolagus cuniculus Q28660 100009397
Bos taurus O77780 281599
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Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017