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Protein Overview: Gamma-glutamylaminecyclotransferase

Contributes to degradation of proteins cross-linked by transglutaminases. Degrades the cross-link between a lysine and a glutamic acid residue from two proteins that have been cross-linked by transglutaminases. Catalyzes the formation of 5-oxoproline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma-glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine.

Synonyms: GGACT, AIG2-like domain-containing protein 1

Gene name: A2LD1

Database References

UniProtID GeneID
Homo sapiens B3KTN1 87769
Xenopus laevis Q66KX0 447124
Bos taurus Q0VFX9 512596
Mus musculus Q66JP0 223267
Rattus norvegicus Q4KM86 290500

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017