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Multidrug resistance-associated protein 1

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Protein Overview: Multidrug resistance-associated protein 1

Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency.

Synonyms: ATP-binding cassette sub-family C member 1, Leukotriene C(4) transporter, LTC4 transporter

Gene name: Abcc1

Database References

UniProtID GeneID
Mus musculus O35379 17250
Gallus gallus Q5F364 395416
Bos taurus Q8HXQ5 281588
Crab-eating macaque Q864R9
Arabidopsis thaliana O24635 839920
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Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017