Negative regulator of the Wnt signaling pathway. Inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin. May act via its interaction with Wnt and LRP proteins. May play a role in colorectal tumorigenesis.
Synonyms: Adenomatosis polyposis coli down-regulated 1 protein homolog
Gene name: Apcdd1
|Western clawed frog||Q6DF34||448576|
|Chinese softshell turtle||Q5R2J4|
Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017