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Putative Polycomb group protein ASXL3

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Protein Overview: Putative Polycomb group protein ASXL3

Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility.

Synonyms: Additional sex combs-like protein 3

Gene name: Asxl3

Database References

UniProtID GeneID
Mus musculus Q8C380 211961
Homo sapiens Q6ZMX6 80816

Protein Overview data has been sourced from Uniprot Consortium's databases under a Creative Commons Attribution-Commercial license. © 2017